Grant #01421

Dr. Stephen A. Kania, PhD
Canine Health Foundation | University of Tennessee
Jan 2011 - $3,000

Jan 2013 - $3,000

Staphylococcal bacteria are responsible for most canine skin infections as well as other important diseases. Until recently antibiotic therapy was very effective for the treatment of these conditions. However, antibiotic resistance is increasing rapidly and we envision running out of useful antibiotic options. Alternatives to antibiotics may include vaccines or bacterial factors naturally produced by staphylococci that inhibit competing strains. The key to developing these strategies is discovering the genes responsible for antibiotic resistance, bacterial growth inhibitors, and targets for vaccines. The first step in our project is the collection of staphylococci causing skin infections from dogs in designated regions throughout the United States. Unique strains of antibiotic resistant bacteria will be identified and their genes of interest characterized for use in the development of the next generation of therapies for the treatment of canine infections.